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Role of the MPTP in conditioning the heart – translatability and mechanism

Mitochondria have long been known to be the gatekeepers of cell fate. This is particularly so in the response to acute ischaemia‐reperfusion injury (IRI). Following an acute episode of sustained myocardial ischaemia, the opening of the mitochondrial permeability transition pore (MPTP) in the first f...

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Bibliografske podrobnosti
izdano v:Br J Pharmacol
Main Authors: Ong, S‐B, Dongworth, R K, Cabrera‐Fuentes, H A, Hausenloy, D J
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386982/
https://ncbi.nlm.nih.gov/pubmed/25393318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13013
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