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Role of the MPTP in conditioning the heart – translatability and mechanism

Mitochondria have long been known to be the gatekeepers of cell fate. This is particularly so in the response to acute ischaemia‐reperfusion injury (IRI). Following an acute episode of sustained myocardial ischaemia, the opening of the mitochondrial permeability transition pore (MPTP) in the first f...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Ong, S‐B, Dongworth, R K, Cabrera‐Fuentes, H A, Hausenloy, D J
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386982/
https://ncbi.nlm.nih.gov/pubmed/25393318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13013
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