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Role of the MPTP in conditioning the heart – translatability and mechanism

Mitochondria have long been known to be the gatekeepers of cell fate. This is particularly so in the response to acute ischaemia‐reperfusion injury (IRI). Following an acute episode of sustained myocardial ischaemia, the opening of the mitochondrial permeability transition pore (MPTP) in the first f...

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Dettagli Bibliografici
Pubblicato in:Br J Pharmacol
Autori principali: Ong, S‐B, Dongworth, R K, Cabrera‐Fuentes, H A, Hausenloy, D J
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386982/
https://ncbi.nlm.nih.gov/pubmed/25393318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13013
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