Advanced glycation end products contribute to amyloidosis in Alzheimer disease.

Alzheimer disease (AD) is characterized by deposits of an aggregated 42-amino-acid beta-amyloid peptide (beta AP) in the brain and cerebrovasculature. After a concentration-dependent lag period during in vitro incubations, soluble preparations of synthetic beta AP slowly form fibrillar aggregates th...

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Publié dans:	Proc Natl Acad Sci U S A
Auteurs principaux:	Vitek, M P, Bhattacharya, K, Glendening, J M, Stopa, E, Vlassara, H, Bucala, R, Manogue, K, Cerami, A
Format:	Artigo
Langue:	Inglês
Publié:	National Academy of Sciences 1994
Sujets:	Research Article
Accès en ligne:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43869/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8197133/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.11.4766
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