Hepatitis C virus RNA functionally sequesters miR-122

Hepatitis C virus uniquely requires the liver specific microRNA-122 for replication, yet global effects on endogenous miRNA targets during infection are unexplored. Here, high-throughput sequencing and crosslinking immunoprecipitation (HITS-CLIP) experiments of human Argonaute (Ago) during HCV infec...

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Publicat a:Cell
Autors principals: Luna, Joseph M., Scheel, Troels K. H., Danino, Tal, Shaw, Katharina S., Mele, Aldo, Fak, John J., Nishiuchi, Eiko, Takacs, Constantin N., Catanese, Maria Teresa, de Jong, Ype P., Jacobson, Ira M., Rice, Charles M., Darnell, Robert B.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386883/
https://ncbi.nlm.nih.gov/pubmed/25768906
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.02.025
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