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Activation of the factor XII-driven contact system in Alzheimer’s disease patient and mouse model plasma

Alzheimer’s disease (AD) is characterized by accumulation of the β-amyloid peptide (Aβ), which likely contributes to disease via multiple mechanisms. Increasing evidence implicates inflammation in AD, the origins of which are not completely understood. We investigated whether circulating Aβ could in...

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Bibliografische gegevens
Gepubliceerd in:Proc Natl Acad Sci U S A
Hoofdauteurs: Zamolodchikov, Daria, Chen, Zu-Lin, Conti, Brooke A., Renné, Thomas, Strickland, Sidney
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: National Academy of Sciences 2015
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386355/
https://ncbi.nlm.nih.gov/pubmed/25775543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423764112
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