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Activation of the factor XII-driven contact system in Alzheimer’s disease patient and mouse model plasma

Alzheimer’s disease (AD) is characterized by accumulation of the β-amyloid peptide (Aβ), which likely contributes to disease via multiple mechanisms. Increasing evidence implicates inflammation in AD, the origins of which are not completely understood. We investigated whether circulating Aβ could in...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Zamolodchikov, Daria, Chen, Zu-Lin, Conti, Brooke A., Renné, Thomas, Strickland, Sidney
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386355/
https://ncbi.nlm.nih.gov/pubmed/25775543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1423764112
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