Two transcription factors, Pou4f2 and Isl1, are sufficient to specify the retinal ganglion cell fate

As with other retinal cell types, retinal ganglion cells (RGCs) arise from multipotent retinal progenitor cells (RPCs), and their formation is regulated by a hierarchical gene-regulatory network (GRN). Within this GRN, three transcription factors—atonal homolog 7 (Atoh7), POU domain, class 4, transc...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Wu, Fuguo, Kaczynski, Tadeusz J., Sethuramanujam, Santhosh, Li, Renzhong, Jain, Varsha, Slaughter, Malcolm, Mu, Xiuqian
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2015
Предметы:
PNAS Plus
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386335/
https://ncbi.nlm.nih.gov/pubmed/25775587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1421535112
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