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Two transcription factors, Pou4f2 and Isl1, are sufficient to specify the retinal ganglion cell fate
As with other retinal cell types, retinal ganglion cells (RGCs) arise from multipotent retinal progenitor cells (RPCs), and their formation is regulated by a hierarchical gene-regulatory network (GRN). Within this GRN, three transcription factors—atonal homolog 7 (Atoh7), POU domain, class 4, transc...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2015
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4386335/ https://ncbi.nlm.nih.gov/pubmed/25775587 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1421535112 |
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