Two transcription factors, Pou4f2 and Isl1, are sufficient to specify the retinal ganglion cell fate

As with other retinal cell types, retinal ganglion cells (RGCs) arise from multipotent retinal progenitor cells (RPCs), and their formation is regulated by a hierarchical gene-regulatory network (GRN). Within this GRN, three transcription factors—atonal homolog 7 (Atoh7), POU domain, class 4, transc...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Wu, Fuguo, Kaczynski, Tadeusz J., Sethuramanujam, Santhosh, Li, Renzhong, Jain, Varsha, Slaughter, Malcolm, Mu, Xiuqian
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2015
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PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4386335/
https://ncbi.nlm.nih.gov/pubmed/25775587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1421535112
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