Autophagy is a regulator of TGF-β(1)-induced fibrogenesis in primary human atrial myofibroblasts

Transforming growth factor-β(1) (TGF-β(1)) is an important regulator of fibrogenesis in heart disease. In many other cellular systems, TGF-β(1) may also induce autophagy, but a link between its fibrogenic and autophagic effects is unknown. Thus we tested whether or not TGF-β(1)-induced autophagy has...

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Bibliografiske detaljer
Udgivet i:Cell Death Dis
Main Authors: Ghavami, S, Cunnington, R H, Gupta, S, Yeganeh, B, Filomeno, K L, Freed, D H, Chen, S, Klonisch, T, Halayko, A J, Ambrose, E, Singal, R, Dixon, I M C
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Original Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385916/
https://ncbi.nlm.nih.gov/pubmed/25789971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cddis.2015.36
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