Autophagy and the unfolded protein response promote profibrotic effects of TGF-β(1) in human lung fibroblasts

Idiopathic pulmonary fibrosis (IPF) is a lethal fibrotic lung disease in adults with limited treatment options. Autophagy and the unfolded protein response (UPR), fundamental processes induced by cell stress, are dysregulated in lung fibroblasts and epithelial cells from humans with IPF. Human prima...

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Detalhes bibliográficos
Publicado no:Am J Physiol Lung Cell Mol Physiol
Main Authors: Ghavami, Saeid, Yeganeh, Behzad, Zeki, Amir A., Shojaei, Shahla, Kenyon, Nicholas J., Ott, Sean, Samali, Afshin, Patterson, John, Alizadeh, Javad, Moghadam, Adel Rezaei, Dixon, Ian M. C., Unruh, Helmut, Knight, Darryl A., Post, Martin, Klonisch, Thomas, Halayko, Andrew J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2018
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5900356/
https://ncbi.nlm.nih.gov/pubmed/29074489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00372.2017
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