Stabilization of LKB1 and Akt by neddylation regulates energy metabolism in liver cancer

The current view of cancer progression highlights that cancer cells must undergo through a post-translational regulation and metabolic reprogramming to progress in an unfriendly environment. In here, the importance of neddylation modification in liver cancer was investigated. We found that hepatic n...

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Pubblicato in:Oncotarget
Autori principali: Barbier-Torres, Lucía, Delgado, Teresa C., García-Rodríguez, Juan L., Zubiete-Franco, Imanol, Fernández-Ramos, David, Buqué, Xabier, Cano, Ainara, Juan, Virginia Gutiérrez-de, Fernández-Domínguez, Itziar, Lopitz-Otsoa, Fernando, Fernández-Tussy, Pablo, Boix, Loreto, Bruix, Jordi, Villa, Erica, Castro, Azucena, Lu, Shelly C., Aspichueta, Patricia, Xirodimas, Dimitris, Varela-Rey, Marta, Mato, José M., Beraza, Naiara, Martínez-Chantar, María L.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Impact Journals LLC 2014
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Research Paper
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385867/
https://ncbi.nlm.nih.gov/pubmed/25650664
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