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Small-RNA loading licenses Argonaute for assembly into a transcriptional silencing complex
Argonautes and their small-RNA cofactors form the core effectors of ancient and diverse gene-silencing mechanisms whose roles include regulation of gene expression and defense against foreign genetic elements. Although Argonautes generally act within multisubunit complexes, what governs their assemb...
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| Veröffentlicht in: | Nat Struct Mol Biol |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4385408/ https://ncbi.nlm.nih.gov/pubmed/25730778 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2979 |
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