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Small-RNA loading licenses Argonaute for assembly into a transcriptional silencing complex

Argonautes and their small-RNA cofactors form the core effectors of ancient and diverse gene-silencing mechanisms whose roles include regulation of gene expression and defense against foreign genetic elements. Although Argonautes generally act within multisubunit complexes, what governs their assemb...

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Detalhes bibliográficos
Publicado no:Nat Struct Mol Biol
Main Authors: Holoch, Daniel, Moazed, Danesh
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385408/
https://ncbi.nlm.nih.gov/pubmed/25730778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2979
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