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Alterations of DNA repair genes in the NCI-60 cell lines and their predictive value for anticancer drug activity
Loss of function of DNA repair (DNAR) genes is associated with genomic instability and cancer predisposition; it also makes cancer cells reliant on a reduced set of DNAR pathways to resist DNA-targeted therapy, which remains the core of the anticancer armamentarium. Because the landscape of DNAR def...
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| Wydane w: | DNA Repair (Amst) |
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| Główni autorzy: | , , , , , , , , , , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
2015
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4385398/ https://ncbi.nlm.nih.gov/pubmed/25758781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2015.01.011 |
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