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Protamine nanoparticles for improving shRNA-mediated anti-cancer effects
Protamine nanoparticles were designed by encapsulating small hairpin RNA (shRNA)-expressing plasmid DNA targeting the Bcl-2 gene (shBcl-2) to silence apoptosis-related Bcl-2 protein for improving the transfection efficiency and cytotoxicity in cancer therapy. Our findings demonstrated that the obtai...
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| Published in: | Nanoscale Res Lett |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Springer US
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4385308/ https://ncbi.nlm.nih.gov/pubmed/25852425 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s11671-015-0845-z |
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