Identifying erlotinib-sensitive non-small cell lung carcinoma tumors in mice using [(11)C]erlotinib PET

BACKGROUND: Non-small cell lung carcinoma (NSCLC) represents approximately 80% of lung cancer cases, and over 60% of these tumors express the epidermal growth factor receptor (EGFR). Activating mutations in the tyrosine kinase (TK) domain of the EGFR are detected in 10% to 30% of NSCLC patients, and...

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Bibliografiske detaljer
Udgivet i:EJNMMI Res
Main Authors: Abourbeh, Galith, Itamar, Batel, Salnikov, Olga, Beltsov, Sergey, Mishani, Eyal
Format: Artigo
Sprog:Inglês
Udgivet: Springer Berlin Heidelberg 2015
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385014/
https://ncbi.nlm.nih.gov/pubmed/25853010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13550-014-0080-0
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