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Loss of MicroRNA-17∼92 in Smooth Muscle Cells Attenuates Experimental Pulmonary Hypertension via Induction of PDZ and LIM Domain 5

Rationale: Recent studies suggest that microRNAs (miRNAs) play important roles in regulation of pulmonary artery smooth muscle cell (PASMC) phenotype and are implicated in pulmonary arterial hypertension (PAH). However, the underlying molecular mechanisms remain elusive. Objectives: This study aims...

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Bibliografiske detaljer
Udgivet i:Am J Respir Crit Care Med
Main Authors: Chen, Tianji, Zhou, Guofei, Zhou, Qiyuan, Tang, Haiyang, Ibe, Joyce Christina F., Cheng, Hongqiang, Gou, Deming, Chen, Ju, Yuan, Jason X.-J., Raj, J. Usha
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384776/
https://ncbi.nlm.nih.gov/pubmed/25647182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201405-0941OC
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