Loss of MicroRNA-17∼92 in Smooth Muscle Cells Attenuates Experimental Pulmonary Hypertension via Induction of PDZ and LIM Domain 5

Rationale: Recent studies suggest that microRNAs (miRNAs) play important roles in regulation of pulmonary artery smooth muscle cell (PASMC) phenotype and are implicated in pulmonary arterial hypertension (PAH). However, the underlying molecular mechanisms remain elusive. Objectives: This study aims...

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Detalhes bibliográficos
Publicado no:Am J Respir Crit Care Med
Main Authors: Chen, Tianji, Zhou, Guofei, Zhou, Qiyuan, Tang, Haiyang, Ibe, Joyce Christina F., Cheng, Hongqiang, Gou, Deming, Chen, Ju, Yuan, Jason X.-J., Raj, J. Usha
Formato: Artigo
Idioma:Inglês
Publicado em: American Thoracic Society 2015
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384776/
https://ncbi.nlm.nih.gov/pubmed/25647182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201405-0941OC
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