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Loss of MicroRNA-17∼92 in Smooth Muscle Cells Attenuates Experimental Pulmonary Hypertension via Induction of PDZ and LIM Domain 5

Rationale: Recent studies suggest that microRNAs (miRNAs) play important roles in regulation of pulmonary artery smooth muscle cell (PASMC) phenotype and are implicated in pulmonary arterial hypertension (PAH). However, the underlying molecular mechanisms remain elusive. Objectives: This study aims...

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Dades bibliogràfiques
Publicat a:Am J Respir Crit Care Med
Autors principals: Chen, Tianji, Zhou, Guofei, Zhou, Qiyuan, Tang, Haiyang, Ibe, Joyce Christina F., Cheng, Hongqiang, Gou, Deming, Chen, Ju, Yuan, Jason X.-J., Raj, J. Usha
Format: Artigo
Idioma:Inglês
Publicat: American Thoracic Society 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384776/
https://ncbi.nlm.nih.gov/pubmed/25647182
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201405-0941OC
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