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Sirtuin inhibitors as anticancer agents

Sirtuins are a class of enzymes with nicotinamide adenine dinucleotide (NAD)-dependent protein lysine deacylase function. By deacylating various substrate proteins, including histones, transcription factors, and metabolic enzymes, sirtuins regulate various biological processes, such as transcription...

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Bibliografische gegevens
Gepubliceerd in:Future Med Chem
Hoofdauteurs: Hu, Jing, Jing, Hui, Lin, Hening
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384657/
https://ncbi.nlm.nih.gov/pubmed/24962284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.14.44
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