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Sirtuin inhibitors as anticancer agents
Sirtuins are a class of enzymes with nicotinamide adenine dinucleotide (NAD)-dependent protein lysine deacylase function. By deacylating various substrate proteins, including histones, transcription factors, and metabolic enzymes, sirtuins regulate various biological processes, such as transcription...
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| Veröffentlicht in: | Future Med Chem |
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| Hauptverfasser: | , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4384657/ https://ncbi.nlm.nih.gov/pubmed/24962284 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.14.44 |
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