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Quantitative analysis of differences in copy numbers using read depth obtained from PCR-enriched samples and controls

BACKGROUND: Next-generation sequencing (NGS) is rapidly becoming common practice in clinical diagnostics and cancer research. In addition to the detection of single nucleotide variants (SNVs), information on copy number variants (CNVs) is of great interest. Several algorithms exist to detect CNVs by...

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發表在:BMC Bioinformatics
Main Authors: Reinecke, Frank, Satya, Ravi Vijaya, DiCarlo, John
格式: Artigo
語言:Inglês
出版: BioMed Central 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384318/
https://ncbi.nlm.nih.gov/pubmed/25626454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-014-0428-5
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