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Detection of copy number variation from array intensity and sequencing read depth using a stepwise Bayesian model
BACKGROUND: Copy number variants (CNVs) have been demonstrated to occur at a high frequency and are now widely believed to make a significant contribution to the phenotypic variation in human populations. Array-based comparative genomic hybridization (array-CGH) and newly developed read-depth approa...
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
BioMed Central
2010
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2992546/ https://ncbi.nlm.nih.gov/pubmed/21034510 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-11-539 |
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