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Quantitative analysis of differences in copy numbers using read depth obtained from PCR-enriched samples and controls

BACKGROUND: Next-generation sequencing (NGS) is rapidly becoming common practice in clinical diagnostics and cancer research. In addition to the detection of single nucleotide variants (SNVs), information on copy number variants (CNVs) is of great interest. Several algorithms exist to detect CNVs by...

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Detaylı Bibliyografya
Yayımlandı:BMC Bioinformatics
Asıl Yazarlar: Reinecke, Frank, Satya, Ravi Vijaya, DiCarlo, John
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2015
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384318/
https://ncbi.nlm.nih.gov/pubmed/25626454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-014-0428-5
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