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NHERFs, NEP, MAGUKs, and More: Interactions That Regulate PTEN

This year marks the 10th anniversary of the discovery of the PTEN/MMAC1/TEP1 tumor suppressor gene (hereafter referred to as PTEN), one of the most commonly mutated genes in cancer. PTEN encodes a lipid phosphatase that dephosphorylates phosphoinositide-3,4,5-triphosphate (PIP(3)), thereby counterac...

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Detalles Bibliográficos
Publicado en:J Cell Biochem
Main Authors: Bonifant, Challice L., Kim, Jung-Sik, Waldman, Todd
Formato: Artigo
Idioma:Inglês
Publicado: 2007
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384183/
https://ncbi.nlm.nih.gov/pubmed/17786934
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.21518
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