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Degradation of βII-Spectrin Protein by Calpain-2 and Caspase-3 under Neurotoxic and Traumatic Brain Injury Conditions

A major consequence of traumatic brain injury (TBI) is the rapid proteolytic degradation of structural cytoskeletal proteins. This process is largely reflected by the interruption of axonal transport as a result of extensive axonal injury leading to neuronal cell injury. Previous work from our group...

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Bibliographic Details
Published in:Mol Neurobiol
Main Authors: Kobeissy, Firas H, Liu, Ming Cheng, Yang, Zhihui, Zhang, Zhiqun, Zheng, Wenrong, Glushakova, Olena, Mondello, Stefania, Anagli, John, Hayes, Ronald L., Wang, Kevin K.W.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383741/
https://ncbi.nlm.nih.gov/pubmed/25270371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12035-014-8898-z
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