Imaging Active Urokinase Plasminogen Activator in Prostate Cancer

The increased proteolytic activity of membrane-bound and secreted proteases on the surface of cancer cells and in the transformed stroma is a common characteristic of aggressive metastatic prostate cancer. We describe here the development of an active site-specific probe for detecting a secreted per...

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Bibliographic Details
Published in:Cancer Res
Main Authors: LeBeau, Aaron M., Sevillano, Natalia, Markham, Kate, Winter, Michael B., Murphy, Stephanie T., Hostetter, Daniel R., West, James, Lowman, Henry, Craik, Charles S., VanBrocklin, Henry F.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383704/
https://ncbi.nlm.nih.gov/pubmed/25672980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-2185
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