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RNA Interference-Directed Knockdown of Urokinase Plasminogen Activator and Urokinase Plasminogen Activator Receptor Inhibits Prostate Cancer Cell Invasion, Survival and Tumorigenicity In vivo

The invasive ability of tumor cells plays a key role in prostate cancer metastasis and is a major cause of treatment failure. Urokinase plasminogen activator (uPA) and its receptor (uPAR)-mediated signaling have been implicated in tumor cell invasion, survival and metastasis in a variety of cancers....

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Main Authors: MuraliKrishna, Pulukuri Sai, Gondi, Christopher S., Lakka, Sajani S., Julta, Aman, Estes, Norman, Gujrati, Meena, Rao, Jasti S.
格式: Artigo
語言:Inglês
出版: 2005
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1351057/
https://ncbi.nlm.nih.gov/pubmed/16127174
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M503111200
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