BRAF Inhibition Stimulates Melanoma-Associated Macrophages to Drive Tumor Growth

PURPOSE: To investigate the roles of melanoma-associated macrophages in melanoma resistance to BRAF inhibitors (BRAFi). EXPERIMENTAL DESIGN: An in vitro macrophage and melanoma cell co-culture system was used to investigate whether macrophages play a role in melanoma resistance to BRAFi. The effects...

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Bibliografiske detaljer
Udgivet i:Clin Cancer Res
Main Authors: Wang, Tao, Xiao, Min, Ge, Yingbin, Krepler, Clemens, Belser, Eric, Lopez-Coral, Alfonso, Xu, Xiaowei, Zhang, Gao, Azuma, Rikka, Liu, Qin, Liu, Rui, Li, Ling, Amaravadi, Ravi K., Xu, Wei, Karakousis, Giorgos, Gangadhar, Tara C., Schuchter, Lynn M., Lieu, Melissa, Khare, Sanika, Halloran, Molly B., Herlyn, Meenhard, Kaufman, Russel E.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383683/
https://ncbi.nlm.nih.gov/pubmed/25617424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-14-1554
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