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G-protein independent coupling of the MC4R to Kir 7.1 in hypothalamic neurons

The regulated release of anorexigenic α-MSH and orexigenic Agouti-related protein (AgRP) from discrete hypothalamic arcuate neurons onto common target sites in the CNS plays a fundamental role in the regulation of energy homeostasis. Both peptides bind with high affinity to the melanocortin-4 recept...

詳細記述

保存先:
書誌詳細
出版年:Nature
主要な著者: Ghamari-Langroudi, Masoud, Digby, Gregory J., Sebag, Julien A., Millhauser, Glenn L., Palomino, Rafael, Matthews, Robert, Gillyard, Taneisha, Panaro, Brandon L., Tough, Iain R., Cox, Helen M., Denton, Jerod S., Cone, Roger D.
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383680/
https://ncbi.nlm.nih.gov/pubmed/25600267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature14051
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