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Targeted Disruption of Protein Kinase Cε Reduces Cell Invasion and Motility through Inactivation of RhoA and RhoC GTPases in Head and Neck Squamous Cell Carcinoma

Over 70% of patients with head and neck squamous cell carcinoma (HNSCC) present with locoregionally advanced stage III and IV disease. In spite of aggressive therapy, locoregional disease recurs in 60% and metastatic disease develops in 15% to 25% of patients causing a major decline in quality and l...

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Bibliografski detalji
Izdano u:Cancer Res
Glavni autori: Pan, Quintin, Bao, Li Wei, Teknos, Theodoros N., Merajver, Sofia D.
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383316/
https://ncbi.nlm.nih.gov/pubmed/17018591
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-06-2646
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