Analysis of T cell receptor beta chains that combine with dominant conserved TRAV5D-4*04 anti-insulin B:9-23 alpha chains

OBJECTIVE: The objective of this study was to define the spectrum of TCR beta chains permissive for T cells with alpha chains containing the conserved TRAV5D-4*04 sequence to target the insulin B:9-23 peptide, a major epitope for initiation of diabetes in the NOD mouse. MATERIALS AND METHODS: We pro...

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Detalhes bibliográficos
Publicado no:J Autoimmun
Main Authors: Zhang, Li, Jasinski, Jean M., Kobayashi, Masakazu, Davenport, Bennett, Johnson, Kelly, Davidson, Howard, Nakayama, Maki, Haskins, Kathryn, Eisenbarth, George S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383244/
https://ncbi.nlm.nih.gov/pubmed/19286348
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2009.02.003
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