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Conserved T cell receptor α-chain induces insulin autoantibodies
A fundamental question is what are the molecular determinants that lead to spontaneous preferential targeting of specific autoantigens in autoimmune diseases, such as the insulin B:9–23 peptide sequence in type 1 diabetes. Anti-insulin B:9–23 T cell clones isolated from prediabetic NOD islets have a...
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| Hlavní autoři: | , , , , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2008
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2464615/ https://ncbi.nlm.nih.gov/pubmed/18626021 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0801648105 |
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