Translation of 5′ leaders is pervasive in genes resistant to eIF2 repression

Eukaryotic cells rapidly reduce protein synthesis in response to various stress conditions. This can be achieved by the phosphorylation-mediated inactivation of a key translation initiation factor, eukaryotic initiation factor 2 (eIF2). However, the persistent translation of certain mRNAs is require...

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Bibliografiska uppgifter
I publikationen:eLife
Huvudupphovsmän: Andreev, Dmitry E, O'Connor, Patrick BF, Fahey, Ciara, Kenny, Elaine M, Terenin, Ilya M, Dmitriev, Sergey E, Cormican, Paul, Morris, Derek W, Shatsky, Ivan N, Baranov, Pavel V
Materialtyp: Artigo
Språk:Inglês
Publicerad: eLife Sciences Publications, Ltd 2015
Ämnen:
Biochemistry
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383229/
https://ncbi.nlm.nih.gov/pubmed/25621764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.03971
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