Post challenge inhibition of C3 and CD14 attenuates Escherichia coli-induced inflammation in human whole blood

Combined inhibition of CD 14 and complement, two main inducers of the inflammatory response, have proved particularly effective in attenuating Gram-negative bacteria-induced inflammation. Approaching possible clinical relevance, we investigated the effect of such inhibition in a post-challenge setti...

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Veröffentlicht in:Innate Immun
Hauptverfasser: Egge, Kjetil H, Thorgersen, Ebbe B, Lindstad, Julie K, Pharo, Anne, Lambris, John D, Barratt-Due, Andreas, Mollnes, Tom E
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383095/
https://ncbi.nlm.nih.gov/pubmed/23669326
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1753425913482993
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