CD14 inhibition efficiently attenuates early inflammatory and hemostatic responses in Escherichia coli sepsis in pigs

Sepsis is a severe infection-induced systemic inflammatory syndrome. Inhibition of downstream inflammatory mediators of sepsis, e.g., TNF-α, has failed in clinical trials. The aim of this study was to investigate the effects of inhibiting CD14, a key upstream innate immunity molecule, on the early i...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Thorgersen, Ebbe Billmann, Hellerud, Bernt Christian, Nielsen, Erik Waage, Barratt-Due, Andreas, Fure, Hilde, Lindstad, Julie Katrine, Pharo, Anne, Fosse, Erik, Tønnessen, Tor Inge, Johansen, Harald Thidemann, Castellheim, Albert, Mollnes, Tom Eirik
Formato: Artigo
Idioma:Inglês
Publicado em: The Federation of American Societies for Experimental Biology 2010
Assuntos:
Research Communications
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2830134/
https://ncbi.nlm.nih.gov/pubmed/19841036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.09-140798
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados