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Ornithodoros moubata complement inhibitor (OmCI) is an equally effective C5 inhibitor in pig and human()

Experimental evidence suggests that C inhibition and more particularly combined inhibition of C and the TLR co-receptor CD14 may be of therapeutic benefit in sepsis and other inflammatory conditions. A barrier to the testing and further development of many inhibitors is that their activity is specie...

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Autores principales: Barratt-Due, Andreas, Thorgersen, Ebbe Billman, Lindstad, Julie Katrine, Pharo, Anne, Lissina, Olga, Lambris, John D., Nunn, Miles A., Mollnes, Tom Eirik
Formato: Artigo
Lenguaje:Inglês
Publicado: 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3359935/
https://ncbi.nlm.nih.gov/pubmed/21964028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1101000
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