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High-resolution structures of kinesin on microtubules provide a basis for nucleotide-gated force-generation

Microtubule-based transport by the kinesin motors, powered by ATP hydrolysis, is essential for a wide range of vital processes in eukaryotes. We obtained insight into this process by developing atomic models for no-nucleotide and ATP states of the monomeric kinesin motor domain on microtubules from...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Shang, Zhiguo, Zhou, Kaifeng, Xu, Chen, Csencsits, Roseann, Cochran, Jared C, Sindelar, Charles V
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4383081/
https://ncbi.nlm.nih.gov/pubmed/25415053
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04686
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