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Structural basis of cooperativity in kinesin revealed by 3D reconstruction of a two-head-bound state on microtubules
The detailed basis of walking by dimeric molecules of kinesin along microtubules has remained unclear, partly because available structural methods have been unable to capture microtubule-bound intermediates of this process. Utilizing novel electron cryomicroscopy methods, we solved structures of mic...
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| Publicado no: | eLife |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5459574/ https://ncbi.nlm.nih.gov/pubmed/28504639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.24490 |
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