Dietary pretreatment with green tea polyphenol, (−)-epigallocatechin-3-gallate reduces the bioavailability and hepatotoxicity of subsequent oral bolus doses of (−)-epigallocatechin-3-gallate()

Human case-studies have reported an association between green tea-based dietary supplements and hepatotoxicity. Studies have demonstrated the hepatotoxicity of high-dose oral bolus dosing with the tea polyphenol (−)-epigallocatechin-3-gallate (EGCG) in mice and dogs. We examined the effect of pretre...

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Bibliografiske detaljer
Udgivet i:	Food Chem Toxicol
Main Authors:	James, Karma D., Forester, Sarah C., Lambert, Joshua D.
Format:	Artigo
Sprog:	Inglês
Udgivet:	2014
Fag:	Article
Online adgang:	https://ncbi.nlm.nih.gov/pmc/articles/PMC4383035/ https://ncbi.nlm.nih.gov/pubmed/25528115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.fct.2014.12.009
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Dietary pretreatment with green tea polyphenol, (−)-epigallocatechin-3-gallate reduces the bioavailability and hepatotoxicity of subsequent oral bolus doses of (−)-epigallocatechin-3-gallate()

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