NOD2 Receptor is Expressed in Platelets and Enhances Platelet Activation and Thrombosis

BACKGROUND: Pattern recognition receptor NOD2 (nucleotide binding oligomerization domain 2) is well investigated in immunity, its expression and function in platelets has never been explored. METHOD AND RESULTS: Using RT-PCR and Western blot we show that both human and mouse platelets express NOD2,...

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Bibliografiska uppgifter
I publikationen:Circulation
Huvudupphovsmän: Zhang, Si, Zhang, Shenghui, Hu, Liang, Zhai, Lili, Xue, Ruyi, Ye, Jianqin, Chen, Leilei, Cheng, Guanjun, Mruk, Jozef, Kunapuli, Satya P., Ding, Zhongren
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382913/
https://ncbi.nlm.nih.gov/pubmed/25825396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.114.013743
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