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Increased platelet activation and thrombosis in transgenic mice expressing constitutively active P2Y(12) receptor
BACKGROUND: In our previous in vitro study we reported a constitutively active chimeric P2Y(12) receptor (cP2Y(12)) and found AR-C78511 is a potent inverse agonist at this receptor. The role of this cP2Y(12) receptor in platelet activation and thrombosis is not clear. OBJECTIVES: To investigate the...
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| Main Authors: | , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3495164/ https://ncbi.nlm.nih.gov/pubmed/22906019 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1538-7836.2012.04894.x |
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