NOD2 Receptor is Expressed in Platelets and Enhances Platelet Activation and Thrombosis

BACKGROUND: Pattern recognition receptor NOD2 (nucleotide binding oligomerization domain 2) is well investigated in immunity, its expression and function in platelets has never been explored. METHOD AND RESULTS: Using RT-PCR and Western blot we show that both human and mouse platelets express NOD2,...

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Publicado no:Circulation
Main Authors: Zhang, Si, Zhang, Shenghui, Hu, Liang, Zhai, Lili, Xue, Ruyi, Ye, Jianqin, Chen, Leilei, Cheng, Guanjun, Mruk, Jozef, Kunapuli, Satya P., Ding, Zhongren
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382913/
https://ncbi.nlm.nih.gov/pubmed/25825396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCULATIONAHA.114.013743
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