Loss of Retinal Cadherin Facilitates Mammary Tumor Progression and Metastasis

The mammary epithelium is thought to be stabilized by cell-cell adhesion mediated mainly by E-cadherin (E-cad). Here, we show that another cadherin, retinal cadherin (R-cad), is critical for maintenance of the epithelial phenotype. R-cad is expressed in nontransformed mammary epithelium but absent f...

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Detalhes bibliográficos
Publicado no:Cancer Res
Main Authors: Agiostratidou, Georgia, Li, Maomi, Suyama, Kimita, Badano, Ines, Keren, Rinat, Chung, Su, Anzovino, Amy, Hulit, James, Qian, Binzhi, Bouzahzah, Boumediene, Eugenin, Eliseo, Loudig, Olivier, Phillips, Greg R., Locker, Joseph, Hazan, Rachel B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382672/
https://ncbi.nlm.nih.gov/pubmed/19491271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-4007
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