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N-cadherin regulates mammary tumor cell migration through Akt3 suppression
N-cadherin is a cell-cell adhesion molecule that plays a role in breast cancer metastasis. Here, we show that in vivo expression of N-cadherin in the PyMT mouse model, which enhances mammary tumor metastasis, results in selective inhibition of Akt3 expression and phosphorylation. Similarly, exogenou...
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| Publicado en: | Oncogene |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4351658/ https://ncbi.nlm.nih.gov/pubmed/22410780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.65 |
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