p21CIP1 mediates reciprocal switching between proliferation and invasion during metastasis

Cell proliferation and invasion are critical for malignant progression, yet how these processes relate to each other and whether they regulate one another during metastasis is unknown. We show that invasiveness of breast cancer cells is associated with growth arrest due to p21CIP1 upregulation. Knoc...

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Udgivet i:Oncogene
Main Authors: Qian, X, Hulit, J, Suyama, K, Eugenin, EA, Belbin, TJ, Loudig, O, Smirnova, T, Zhou, ZN, Segall, J, Locker, J, Phillips, GR, Norton, L, Hazan, RB
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350674/
https://ncbi.nlm.nih.gov/pubmed/22751124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.249
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