p21CIP1 mediates reciprocal switching between proliferation and invasion during metastasis

Cell proliferation and invasion are critical for malignant progression, yet how these processes relate to each other and whether they regulate one another during metastasis is unknown. We show that invasiveness of breast cancer cells is associated with growth arrest due to p21CIP1 upregulation. Knoc...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Qian, X, Hulit, J, Suyama, K, Eugenin, EA, Belbin, TJ, Loudig, O, Smirnova, T, Zhou, ZN, Segall, J, Locker, J, Phillips, GR, Norton, L, Hazan, RB
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4350674/
https://ncbi.nlm.nih.gov/pubmed/22751124
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.249
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