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Small Molecule Chemical Probes of MicroRNA Function

MicroRNAs (miRNAs) are small, non-coding RNAs that control protein expression. Aberrant miRNA expression has been linked to various human diseases, and thus miRNAs have been explored as diagnostic markers and therapeutic targets. Although it is challenging to target RNA with small molecules in gener...

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Detalles Bibliográficos
Publicado en:Curr Opin Chem Biol
Main Authors: Velagapudi, Sai Pradeep, Vummidi, Balayeshwanth R., Disney, Matthew D.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382669/
https://ncbi.nlm.nih.gov/pubmed/25500006
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbpa.2014.10.024
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