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Improving Prediction of Carcinogenicity to Reduce, Refine, and Replace the Use of Experimental Animals

Cancer risk assessment of new pharmaceuticals is crucial to protect public health. However, clinical trials lack the duration needed to clearly detect drug-related tumor emergence, and biomarkers suggestive of increased cancer risk from a drug typically are not measured in clinical trials. Therefore...

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書誌詳細
出版年:J Am Assoc Lab Anim Sci
主要な著者: Bourcier, Todd, McGovern, Tim, Stavitskaya, Lidiya, Kruhlak, Naomi, Jacobson-Kram, David
フォーマット: Artigo
言語:Inglês
出版事項: American Association for Laboratory Animal Science 2015
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382620/
https://ncbi.nlm.nih.gov/pubmed/25836962
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