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Improving Prediction of Carcinogenicity to Reduce, Refine, and Replace the Use of Experimental Animals

Cancer risk assessment of new pharmaceuticals is crucial to protect public health. However, clinical trials lack the duration needed to clearly detect drug-related tumor emergence, and biomarkers suggestive of increased cancer risk from a drug typically are not measured in clinical trials. Therefore...

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Опубликовано в: :J Am Assoc Lab Anim Sci
Главные авторы: Bourcier, Todd, McGovern, Tim, Stavitskaya, Lidiya, Kruhlak, Naomi, Jacobson-Kram, David
Формат: Artigo
Язык:Inglês
Опубликовано: American Association for Laboratory Animal Science 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4382620/
https://ncbi.nlm.nih.gov/pubmed/25836962
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